The Gene

The Gene Author Siddhartha Mukherjee
ISBN-10 9781476733531
Year 2016-05-17
Pages 608
Language en
Publisher Simon and Schuster
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THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The dark summer

The dark summer Author Gene Smith
ISBN-10 0020373902
Year 1989-04-01
Pages 314
Language en
Publisher Simon & Schuster Books For Young Readers
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An account that focuses on the month of 1939 preceding the declaration of war.

The Laws of Medicine

The Laws of Medicine Author Siddhartha Mukherjee
ISBN-10 9781476784854
Year 2015-10-13
Pages 96
Language en
Publisher Simon and Schuster
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Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

Woman

Woman Author Natalie Angier
ISBN-10 9781844089918
Year 2014-08-07
Pages 560
Language en
Publisher Hachette UK
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WOMAN explores the essence of what it means to be female. In mapping the inner woman - from organs to orgasms - Natalie Angier presents an extraordinary new vision of the female body as an evolutionary masterpiece. 'Anyone living in or near a female body should read this book' - Gloria Steinem 'Women have long been regarded as slaves to biology and evolution, prisoners in a hormonal swamp. But now, some of the sacred tenets of evolutionary psychology . . . have come under fresh challenge. As the century turns, it could be Goodbye women's lib; hello female liberation! . . . WOMAN is a delicious cocktail of estrogen and amphetamine designed to pump up the ovaries as well as the cerebral cortex' - Barbara Ehrenreich, Time magazine 'Drawing on science, literature and history, Angier provides valuable insight into the power of hormones, breast milk and the all-important clitoris. A must for every woman's bookshelf' - Woman's Journal

A Crack in Creation

A Crack in Creation Author Jennifer A. Doudna
ISBN-10 9780544716964
Year 2017-06-13
Pages 320
Language en
Publisher Houghton Mifflin Harcourt
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A trailblazing biologist grapples with her role in the biggest scientific discovery of our era: a cheap, easy way of rewriting genetic code, with nearly limitless promise and peril. Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers, and will help address the world’s hunger crisis. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Samuel Sternberg, Doudna shares the thrilling story of her discovery, and passionately argues that enormous responsibility comes with the ability to rewrite the code of life. With CRISPR, she shows, we have effectively taken control of evolution. What will we do with this unfathomable power?

The Emperor of All Maladies

The Emperor of All Maladies Author Siddhartha Mukherjee
ISBN-10 9781439170915
Year 2011-08-09
Pages 573
Language en
Publisher Simon and Schuster
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An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.

The Age of Genomes

The Age of Genomes Author Steven Monroe Lipkin
ISBN-10 9780807074572
Year 2016-05-17
Pages 256
Language en
Publisher Beacon Press
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A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history Almost every week, another exciting headline appears about new advances in the field of genetics. Genetic testing is experiencing the kind of exponential growth once seen with the birth of the Internet, while the plummeting cost of DNA sequencing makes it increasingly accessible for individuals and families. Steven Lipkin and Jon Luoma posit that today's genomics is like the last century's nuclear physics: a powerful tool for good if used correctly, but potentially dangerous nonetheless. DNA testing is likely the most exciting advance in a long time for treating serious disease, but sequencing errors, complex biology, and problems properly interpreting genetic data can also cause life-threatening misdiagnoses of patients with debilitating and fatal genetic diseases. DNA testing can also lead to unnecessary procedures and significantly higher health-care costs. And just around the corner is the ability to cure genetic diseases using powerful gene-editing technologies that are already being used in human embryo research. Welcome to the Age of Genomes! The Age of Genomes immerses readers in true stories of patients on the frontier of genomic medicine and explores both the transformative potential and risks of genetic technology. It will inform anxious parents increasingly bombarded by offers of costly new prenatal testing products, and demonstrate how genetic technology, when deployed properly, can significantly improve the lives of patients who have devastating neurological diseases, cancer, and other maladies. Dr. Lipkin explains the science in depth, but in terms a layperson can follow.

Mr Todiwala s Spice Box

Mr Todiwala s Spice Box Author Cyrus Todiwala
ISBN-10 9781784721817
Year 2016-06-02
Pages 240
Language en
Publisher Hachette UK
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Cyrus Todiwala is known for combining flavours, spices and ingredients in ways no other Indian chef has ever done before. He loves mixing Western dishes with Indian flavourings to create recipes that make innovative and delicious use of spices. Offering an entirely fresh look at spices, Cyrus takes just 10 of his favourites and bases 120 recipes around them. Using his special spice box and a selection of fresh ingredients, he conjures up an astonishing range of dishes that will spice up any mealtime, such as Prawn & Crab Masala Omelette, Venison Kebabs, Garlic & Red Chilli Chicken, Hot Smoked Salmon Tikka and Saffron & Cardamom Crème Brûlée.

Telling Genes

Telling Genes Author Alexandra Minna Stern
ISBN-10 9781421407487
Year 2012-08-31
Pages 248
Language en
Publisher JHU Press
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For sixty years genetic counselors have served as the messengers of important information about the risks, realities, and perceptions of genetic conditions. More than 2,500 certified genetic counselors in the United States work in clinics, community and teaching hospitals, public health departments, private biotech companies, and universities. Telling Genes considers the purpose of genetic counseling for twenty-first century families and society and places the field into its historical context. Genetic counselors educate physicians, scientific researchers, and prospective parents about the role of genetics in inherited disease. They are responsible for reliably translating test results and technical data for a diverse clientele, using scientific acumen and human empathy to help people make informed decisions about genomic medicine. Alexandra Minna Stern traces the development of genetic counseling from the eugenics movement of the early twentieth century to the current era of human genomics. Drawing from archival records, patient files, and oral histories, Stern presents the fascinating story of the growth of genetic counseling practices, principles, and professionals. -- Troy Duster, Chancellor's Professor and Senior Fellow, Warren Institute on Law and Social Policy, University of California, Berkeley

Behave

Behave Author Robert M. Sapolsky
ISBN-10 9780735222786
Year 2017-05-02
Pages 800
Language en
Publisher Penguin
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Why do we do the things we do? Over a decade in the making, this game-changing book is Robert Sapolsky's genre-shattering attempt to answer that question as fully as perhaps only he could, looking at it from every angle. Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its genetic inheritance. And so the first category of explanation is the neurobiological one. What goes on in a person's brain a second before the behavior happens? Then he pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell triggers the nervous system to produce that behavior? And then, what hormones act hours to days earlier to change how responsive that individual is to the stimuli which trigger the nervous system? By now, he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened. Sapolsky keeps going--next to what features of the environment affected that person's brain, and then back to the childhood of the individual, and then to their genetic makeup. Finally, he expands the view to encompass factors larger than that one individual. How culture has shaped that individual's group, what ecological factors helped shape that culture, and on and on, back to evolutionary factors thousands and even millions of years old. The result is one of the most dazzling tours de horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

The Culture of Fashion

The Culture of Fashion Author Christopher Breward
ISBN-10 0719041252
Year 1995-05-15
Pages 244
Language en
Publisher Manchester University Press
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This illustrated survey of 600 years of fashion investigates its cultural and social meaning from medieval Europe to twentieth-century America. Breward's work provides the reader with a clear guide to the changes in style and taste and shows that clothes have always played a pivotal role in defining a sense of identity and society, especially when concerned with sexual and body politics.

A Brief History of Everyone Who Ever Lived

A Brief History of Everyone Who Ever Lived Author Adam Rutherford
ISBN-10 9780297609391
Year 2016-09-08
Pages 432
Language en
Publisher Hachette UK
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This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species - births, deaths, disease, war, famine, migration and a lot of sex. Since scientists first read the human genome in 2001 it has been subject to all sorts of claims, counterclaims and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be.

Meathooked

Meathooked Author Marta Zaraska
ISBN-10 9780465098729
Year 2016-02-23
Pages 272
Language en
Publisher Hachette UK
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A few years ago, Marta Zaraska's mother decided to go vegetarian after stumbling upon an article on the health risks of eating meat. Her resolve lasted about a fortnight before the juicy hams and the creamy pâtés began creeping back into her refrigerator. Prodded to explain her lapse, she replied, “I like meat, I eat it, end of story.” Many of us have had a similar experience. What makes us crave animal protein, and what makes it so hard to give up? And if all the studies are correct, and consuming meat is truly unhealthy for us, why didn't evolution turn us all into vegetarians in the first place? In Meathooked, Zaraska explores what she calls the “meat puzzle”: our love of meat, despite its harmful effects. Scientific journals overflow with reports of red meat raising the risk of certain cancers; each hamburger contributes as much to global warming as does driving a car 320 miles; and the horrors of industrial meat production are now well-known. None of these facts have prompted us to give up our hamburgers and steaks. On the contrary, meat consumption has only increased over the past decades. Taking the reader to India's unusual steakhouses, animal sacrifices at temples in Benin, and labs in Pennsylvania where meat is being grown in petri dishes, Zaraska examines the history and future of meat and meat-eating, showing that while our increasing consumption of meat can be attributed in part to the power of the meat industry and the policies of our governments, the main “hooks” that keep us addicted to meat are much older: genes and culture. An original and thought-provoking exploration of carnivorousness, Meathooked explains one of the most enduring features of human civilization—and why meat-eating will continue to shape our bodies and our world into the foreseeable future.

I Contain Multitudes

I Contain Multitudes Author Ed Yong
ISBN-10 9781473520189
Year 2016-09-01
Pages 368
Language en
Publisher Random House
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Selected as a Non-Fiction Book of the Year New York Times Selected as a Science Book of the Year by The Economist, The Times and Observer NEW YORK TIMES BESTSELLER Your body is teeming with tens of trillions of microbes. It’s an entire world, a colony full of life. In other words, you contain multitudes. These microscopic companions sculpt our organs, protect us from diseases, guide our behaviour, and bombard us with their genes. They also hold the key to understanding all life on earth. In I Contain Multitudes, Ed Yong opens our eyes and invites us to marvel at ourselves and other animals in a new light, less as individuals and more as thriving ecosystems. We learn the invisible and wondrous science behind the corals that construct mighty reefs and the squid that create their own light shows. We see how bacteria can alter our response to cancer-fighting drugs, tune our immune system, influence our evolution, and even modify our genetic make-up. And we meet the scientists who are manipulating these microscopic partners to our advantage. In a million tiny ways, I Contain Multitudes will radically change how you think about the natural world, and how you see yourself.

The dark summer

The dark summer Author Gene Smith
ISBN-10 0020373902
Year 1989-04-01
Pages 314
Language en
Publisher Simon & Schuster Books For Young Readers
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An account that focuses on the month of 1939 preceding the declaration of war.